Welcome to The Gould LabWe are interested in how the environment shapes our physiology and metabolism and how this impacts upon health and disease. Research focuses on identifying the protective mechanisms that allow developing and adult animals to cope with environmental challenges such as malnutrition and oxidative stress. This research also aims to shed light on the complex interactions between environmental factors and the genes influencing metabolic and age-related diseases.
Much of our research utilises the fruit fly Drosophila, a model organism that shares many genes with humans and has contributed to our understanding of several different aspects of health and disease. We are also following up some of our most significant Drosophila findings in mammalian models. The lab uses a wide variety of experimental approaches including genetics, confocal microscopy, imaging mass spectrometry and metabolomics.
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Latest newsMar 2020: Coronavirus cancels multiple meetings. Our lab trip to BSDB/GenSoc2020 in Warwick was cancelled, as well as Alex’s plenary talk at The Allied Genetics Conference 2020 in Washington DC. Jan 2020: Congratulations to Ying Zhang who starts her Sir Henry Wellcome Postdoctoral Fellowship on "Mechanisms of stress-induced brain sparing during development” Dec 2019: Clare Newell’s preprint on a new cryogenic method for mass spectrometry imaging is now out at BioRxiv. |
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