Welcome to The Gould LabWe are interested in how the environment shapes our physiology and metabolism and how this impacts upon health and disease. Research focuses on identifying the protective mechanisms that allow developing and adult animals to cope with environmental challenges such as malnutrition and oxidative stress. This research also aims to shed light on the complex interactions between environmental factors and the genes influencing metabolic and age-related diseases.
Much of our research utilises the fruit fly Drosophila, a model organism that shares many genes with humans and has contributed to our understanding of several different aspects of health and disease. We are also following up some of our most significant Drosophila findings in mammalian models. The lab uses a wide variety of experimental approaches including genetics, confocal microscopy, imaging mass spectrometry and metabolomics.
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Latest newsNov 2020: Ola Lubojemska’s preprint on the function of lipid droplets in Drosophila renal cells is now out at bioRxiv Sep 2020: Congratulations to Adrien Franchet, named researcher on a new project grant to build An atlas of the stressed fly brain Aug 2020: Congratulations to Clare Newell on her Cryogenic OrbiSIMS paper now out at Angewandte Chemie with more info on the Crick and National Physical Laboratory websites. |
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