Welcome to The Gould Lab
We are interested in how the environment shapes our physiology and metabolism and how this impacts upon health and disease. Research focuses on identifying the protective mechanisms that allow developing and adult animals to cope with environmental challenges such as malnutrition and oxidative stress. This research also aims to shed light on the complex interactions between environmental factors and the genes influencing metabolic and age-related diseases.
Much of our research utilises the fruit fly Drosophila, a model organism that shares many genes with humans and has contributed to our understanding of several different aspects of health and disease. We are also following up some of our most significant Drosophila findings in mammalian models. The lab uses a wide variety of experimental approaches including genetics, confocal microscopy, imaging mass spectrometry and metabolomics.
Mar 2018: Oxidants in early life increase fruit fly lifespan via the microbiome. Congratulations to Fumiaki Obata and Clara Fons on their new paper in Nature Communications.
Feb 2018: Applications are invited for a new postdoctoral research post on the developmental origins of health and longevity. Closing date 19-Mar-2018
More details and to apply
Dec 2017: Congratulations to André Eid on his EMBO Long Term Fellowship for postdoctoral research in the lab.
Nov 2017: Discussion of developmental nutrition and lifespan with Alex, interviewed by Georgia Mills of “The Naked Scientists” for BBC Radio 5 Live on 26th Nov 2017